Reviewed
Homo Sapiens (Human) [TaxID: 9606]
ORF6
DNA primase (EC 2.7.7.-)
Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Varicellovirus> Human Herpesvirus 3 (HHV-3) (Varicella-zoster Virus)> Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Various pathway(s) in which protein is involved
Not Available
Not Available
MDKSSKPTIRLLFATKGCAISHSLLLLTGQISTEPLYVVSYTWTPDLDDVFVKNGREEITQVIPTKRPREVTENDEENQIMHLFCSRDVNVIFYLIGGFS
TGDVRSRVWPIFFCCFKTQTDFKALYKALWYGAPLNPHIISDTLCISETFDIHSEVIQTLMVTTHHLNRKGLSDNGLCITEATLCKLVKKSVGRQELTSL
YAHYERQVLAAYRRLYWGYGCSPFWYIVRFGPSEKTLVLATRYYLLQTDTSYNTLETPLYDLQAIKDLFLTYQVPALPNCSGYNISDLLSFDKLSMFCCS
STYTRGLTAKNALSYILQRIHTDTTEIHAVSEYITNDRKGLKVPDREFVDYIYLAHFECFNRKQIADHLQAVTYSDFVNKPVLLKSSNLGKRATANFFNH
VRSRLNMRDYIKKNVICDVTELGPEIGHKYTITKTYTLSLTYAAKPSKFIGVCDLATTLTRRVENIEKQFSPYGWSSTIPSNPPGFDELSNFEDSGVSAE
ALRAANFANDTPNQSGRTGFDTSPGITKLLLFFSAATGIATHDVSILSYKTPLEALIGHSEVTGPMPVYRVALPHGAQAFAVIANDTWSSITNRYTLPHE
ARLIAEDLKQINPCNFVAASLRDMQLTLLLSTSVKNVSKISSNIPKDQLYINRNELFNTNLIITNLILDVDFHIRKPIPLGILHAGMRAFRHGILTAMQL
LFPKAVVNPNKDPCYFYKTACPEPTVEVLDDDNLLDITSHSDIDFYIENGELYTCVEENYTEDVWFFDTQTTSEVHTHADVSNNENLHETLPCNCKEKIG
FRVCVPIPNPYALVGSSTLKGFAQILQQAVLLEREFVEYIGPYLRDFSFIDTGVYSHGHSLRLPFFSKVTTTGTAVGQLLPFYVVPEQCIDILAFVTSHR
NPANFHFHSRPQSNVPVQFILHNLGGEYAEFFERKVARNKQIFSSPQISLTKALKERGVTCLDAFTLEAFVDSTILESIVEHIAVHFPGRDREYTLTSSK
CIAIKRDWVLFQLICGTKGFTCLRYPHRGGRTAPRTFVSLRVDHHNRLCISLAQQCFATKCDSNRMHTIFTLEVPNYPNLTSS
TGDVRSRVWPIFFCCFKTQTDFKALYKALWYGAPLNPHIISDTLCISETFDIHSEVIQTLMVTTHHLNRKGLSDNGLCITEATLCKLVKKSVGRQELTSL
YAHYERQVLAAYRRLYWGYGCSPFWYIVRFGPSEKTLVLATRYYLLQTDTSYNTLETPLYDLQAIKDLFLTYQVPALPNCSGYNISDLLSFDKLSMFCCS
STYTRGLTAKNALSYILQRIHTDTTEIHAVSEYITNDRKGLKVPDREFVDYIYLAHFECFNRKQIADHLQAVTYSDFVNKPVLLKSSNLGKRATANFFNH
VRSRLNMRDYIKKNVICDVTELGPEIGHKYTITKTYTLSLTYAAKPSKFIGVCDLATTLTRRVENIEKQFSPYGWSSTIPSNPPGFDELSNFEDSGVSAE
ALRAANFANDTPNQSGRTGFDTSPGITKLLLFFSAATGIATHDVSILSYKTPLEALIGHSEVTGPMPVYRVALPHGAQAFAVIANDTWSSITNRYTLPHE
ARLIAEDLKQINPCNFVAASLRDMQLTLLLSTSVKNVSKISSNIPKDQLYINRNELFNTNLIITNLILDVDFHIRKPIPLGILHAGMRAFRHGILTAMQL
LFPKAVVNPNKDPCYFYKTACPEPTVEVLDDDNLLDITSHSDIDFYIENGELYTCVEENYTEDVWFFDTQTTSEVHTHADVSNNENLHETLPCNCKEKIG
FRVCVPIPNPYALVGSSTLKGFAQILQQAVLLEREFVEYIGPYLRDFSFIDTGVYSHGHSLRLPFFSKVTTTGTAVGQLLPFYVVPEQCIDILAFVTSHR
NPANFHFHSRPQSNVPVQFILHNLGGEYAEFFERKVARNKQIFSSPQISLTKALKERGVTCLDAFTLEAFVDSTILESIVEHIAVHFPGRDREYTLTSSK
CIAIKRDWVLFQLICGTKGFTCLRYPHRGGRTAPRTFVSLRVDHHNRLCISLAQQCFATKCDSNRMHTIFTLEVPNYPNLTSS
1083
Not Available
Not Available
01-07-1989
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Essential component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
2.7.7.-
Host nucleus . Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus. .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available