Results | viHumans

UniProt ID

P06942

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

M

Protein Name

Matrix protein

Organism Name

Measles Virus (strain Edmonston) (MeV) (Subacute Sclerose Panencephalitis Virus)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Morbillivirus> Measles Morbillivirus> Measles Virus (strain Edmonston) (MeV) (Subacute Sclerose Panencephalitis Virus)

RefSeq

NC_001498.1 ; AB016162.1

PubMed ID

3754588 ; 2596022

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MTEIYDFDKSAWDIKGSIAPIQPTTYSDGRLVPQVRVIDPGLGDRKDECFMYMFLLGVVEDSDPLGPPIGRAFGSLPLGVGRSTAKPEKLLKEATELDIV
VRRTAGLNEKLVFYNNTPLTLLTPWRKVLTTGSVFNANQVCSAVNLIPLDTPQRFRVVYMSITRLSDNGYYTVPRRMLEFRSVNAVAFNLLVTLRIDKAI
GPGKIIDNTEQLPEATFMVHIGNFRRKKSEVYSADYCKMKIEKMGLVFALGGIGGTSLHIRSTGKMSKTLHAQLGFKKTLCYPLMDINEDLNRLLWRSRC
KIVRIQAVLQPSVPQEFRIYDDVIINDDQGLFKVL
						

Length

335

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-01-1988

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.

EC

Not Available

Experimentally known GO terms

GO:0019013 ; GO:0019031 ; GO:0019068 ; GO:0039660

Subcellular Location

Virion .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available